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Definition and biological significance of the major histocompatibility system (MHS) in man and animals

Authors
Journal
Veterinary Immunology and Immunopathology
0165-2427
Publisher
Elsevier
Publication Date
Volume
2
Issue
6
Identifiers
DOI: 10.1016/0165-2427(81)90013-1
Disciplines
  • Medicine

Abstract

Abstract Already for some time the major histocompatibility system (MHS) is no longer considered to be only of importance in transplantation surgery. The MHS might also partly control specific immune responsiveness. In fact, tissue antigens may serve as a marker system for individual immunocompetence. So, in veterinary relevant species, tissue typing could be an important tool in breeding and health programs. The purpose of this review is to summarize the current knowledge of the MHS in different species.

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