Abstract Non-coring based exploratory drilling was under taken in the sedimentary environment of Rangsohkham block, East Khasi Hills district to examine the eastern extension of existing uranium resources located at Domiasiat and Wakhyn in the Mahadek basin of Meghalaya (India). Although radiometric survey and radiometric analysis of surface grab/channel samples in the block indicate high uranium content but the gamma ray logging results of exploratory boreholes in the block, did not obtain the expected results. To understand this abrupt discontinuity between the two sets of data (surface and subsurface) multivariate statistical analysis of primordial radioactive elements (K40, U238 and Th232) was performed using the concept of representative subsurface samples, drawn from the randomly selected 11 boreholes of this block. The study was performed to a high confidence level (99%), and results are discussed for assessing the U and Th behavior in the block. Results not only confirm the continuation of three distinct geological formations in the area but also the uranium bearing potential in the Mahadek sandstone of the eastern part of Mahadek Basin.