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Infecciones producidas por los virus de la gripe aviar A (H5N1) en las poblaciones de aves del sudeste asiático y en la especie humana

Authors
Journal
Enfermedades Infecciosas y Microbiología Clínica
0213-005X
Publisher
Elsevier
Volume
22
Issue
7
Identifiers
DOI: 10.1016/s0213-005x(04)73124-9
Keywords
  • Gripe Aviar
  • Influenza A(H5N1)
  • Factores De Virulencia
  • Evolución De Virus Influenza
  • Avian Influenza
  • Virulence Factors
  • Influenza Evolution
Disciplines
  • Medicine

Abstract

Avian influenza affects most types of birds and occurs in epidemics on poultry farms. The fatal disease is named “highly pathogenic avian influenza” and is caused by influenza A virus subtypes H5 and H7. The natural reservoir is the migratory waterfowl that occasionally infects domestic poultry. In 1997 in Hong Kong, 18 persons were infected and 6 of them died. At the end of 2003 and the beginning of 2004, avian influenza H5N1 infected numerous farms in several South-Eastern Asian countries. The virus was transmitted to humans in close contact with infected birds. A total of 34 persons were infected and 23 of them died. There is currently a considerable concern about the H5N1 avian influenza that has infected humans: the high virulence, evolution rate, the possibility of recombination with other influenza viruses, how H5N1 variants that infect humans or different approaches to the development of influenza vaccines.

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