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Antimicrobial resistance in gram-negative bacteria isolated from the urinary tract in community-residing persons with spinal cord injury

Authors
Journal
Archives of Physical Medicine and Rehabilitation
0003-9993
Publisher
Elsevier
Volume
81
Issue
6
Identifiers
DOI: 10.1016/s0003-9993(00)90108-4
Keywords
  • Spinal Cord Injuries
  • Urinary Tract Infections
  • Bacteriuria
  • Drug Resistance Microbial
  • Rehabilitation
Disciplines
  • Biology
  • Medicine

Abstract

Abstract Objective: To assess the epidemiology of antimicrobial resistance among community-residing persons with spinal cord injury (SCI). Design: Retrospective analysis of existing data. Setting: Data were obtained from persons with SCI attending clinic for annual examinations. Participants: Two hundred eighty-seven SCI outpatients. Intervention: None. Main Outcome Measure: Occurrence of bacteriuria with gram-negative organisms demonstrating resistance to antimicrobial agents in 2 or more classes. Results: There were 706 gram-negative isolates from 444 urine specimens. Resistance to drugs in 2 or more classes occurred in 33% of bacterial isolates, but did not significantly increase in frequency among those injured for longer periods or more severely. Significantly higher rates of multidrug-resistant bacteria occurred in specimens from males, younger age group (≤45 yrs), and persons with indwelling and condom catheters. Conclusions: Antimicrobial resistance in outpatients with SCI is common and is related to widespread use of specific drugs, type of bladder management, and other host factors.

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