Abstract Introduction The aim of this case report is to present a patient with pulmonary embolism during a high dose course of panax. Case A forty-one year old woman was admitted to the emergency department with sudden complaints of shortness of breath, sweating, weakness and loss of conscious after panax pills intake. At pulmonary CT angiography hypodense filling defect compatible with pulmonary emboli was seen at the bifurcation level of right and left distal pulmonary arteries and at each of pulmonary lobary arteries. Patient treated with pulmonary artery selective thrombolysis. Conclusion Herbal products which are used in all over the world to support health should not be taken indiscriminately because their ingredients' amounts and what kind of adverse effects may come up whether used alone or in combination can’t be known.