Affordable Access

RNAs from genetically distinct retroviruses can copackage and exchange genetic information in vivo.

Authors
Publication Date
Source
PMC
Keywords
  • Research Article

Abstract

Sequence analysis suggests that ancient recombination events may have occurred between genetically distinct retroviruses. An experimental system was utilized to explore the genetic interaction between different viruses. Moloney murine sarcoma virus and spleen necrosis virus are type C retroviruses that belong to different subgenera. With vectors containing packaging signals from these two viruses, DNA proviruses containing genetic information from both RNAs can be generated. This is the first experimental evidence to indicate that RNA from different retroviruses can copackage and exchange genetic information.

There are no comments yet on this publication. Be the first to share your thoughts.