Perhaps in no other disease is the interplay between psychiatry and medicine as well illustrated as in anorexia nervosa (AN) and bulimia nervosa (BN). The diagnostic criteria of AN mandate that a woman must have fallen below 85% of her expected body weight and have ceased menstruating for three consecutive cycles, 1 both physical manifestations of a complex underlying psychological process. When the pursuit of thinness becomes all consuming and weight loss is achieved by extreme dieting, exercising, or use of purgatives, diuretics, and laxatives, or associated with binge behavior, medical complications become apparent that, if unrecognized, may lead to death. The reported mortality rate of AN ranges from 0% to 22%. 66,72 We review the medical complications associated with eating disorders and offer guidelines that may be used in the medical evaluation and treatment of eating-disorder patients.