Summary Among the staff of an intensive care unit which has been in charge of more than 400 HIV patients over a period of 6 years, no seroconversion case was observed. Due precautions were taken in respect of staff outfit in certain cases, but they mostly concerned blood specimen collection and materials : single use apparatus for aspiration, filters on respirators. Eye and nose protection with glasses and mask is compulsory whenever clinical practice exposes to projections. The frequency of casual wounds is estimated to be in the range of 0.7 and 2.4 accidents per year and per nurse. The advisability of transferring certain cases of AIDS to an intensive care unit was discussed. The disease's letality in the hospital reaches 50 % at this stage. The median of life expectancy for these 50 % who leave the hospital is 7.3 months. However, as the epidemia is still developing, a growing need for hospital beds and adapted support has to be foreseen.