Affordable Access

Bacterial Endosymbionts of Free-living Amoebae1

Authors
Publisher
International Society of Protistologists
Publication Date

Abstract

Abstract The occurrence of bacterial endosymbionts in free-living amoebae has been known for decades, but their obligate intracellular lifestyle hampered their identification. Application of the full cycle rRNA approach, including 16S rRNA gene sequencing and fluorescence in-situ hybridization with 16S rRNA-targeted oligonucleotide probes, assigned the symbionts of Acanthamoeba spp. and Hartmannella sp. to five different evolutionary lineages within the Proteobacteria, the Bacteroidetes, and the Chlamydiae, respectively. Some of these bacterial symbionts are most closely related to bacterial pathogens of humans, and it has been suggested that they should be considered potential emerging pathogens. Complete genome sequence analysis of a chlamydia-related symbiont of Acanthamoeba sp. showed that this endosymbiont uses similar mechanisms for interaction with its eukaryotic host cell as do the well-known bacterial pathogens of humans. Furthermore, phylogenetic analysis suggested that these mechanisms have been evolved by the ancestor of these amoeba symbionts in interplay with ancient unicellular eukaryotes.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Bacterial infections of free-living amoebae

on Research in Microbiology Jan 01, 2001

Bacterial infections of free-living amoebae.

on Research in Microbiology September 2001

Growth of small free-living amoebae in various bac...

on Canadian Journal of Microbiolo... August 1960

Pathogenic free-living amoebae.

on The Lancet Dec 03, 1977
More articles like this..