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BELFAST nonagenarians: nature or nurture? Immunological, cardiovascular and genetic factors

Authors
Journal
Immunity & Ageing
1742-4933
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Volume
7
Issue
1
Identifiers
DOI: 10.1186/1742-4933-7-6
Keywords
  • Review
Disciplines
  • Medicine

Abstract

Nonagenarians are the fastest growing sector of populations across Western European and the developed world. They are some of the oldest members of our societies and survivors of their generation and may help us understand how to age not only longer, but better. The Belfast Longevity Group enlisted the help of 500 community-living, mobile, mentally competent, 'elite' nonagenarians, as part of an ongoing study of ageing. We assessed some immunological, cardiovascular, nutritional and genetic factors and some aspects of their interaction in this group of 'oldest old'. Here we present some of the evidence related to genetic and nutritional factors which seem to be important for good quality ageing in nonagenarians from the Belfast Elderly Longitudinal Free-living Ageing STudy (BELFAST).

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