Affordable Access

Successful occlusion therapy of amblyopia in 11- to 15-year-old children

American Journal of Ophthalmology
Publication Date
DOI: 10.1016/j.ajo.2004.07.018
  • Medicine


A prospective, single-center study was conducted to investigate the effectiveness and lasting effect of full-time occlusion therapy in treating amblyopia in 11- to 15-year-old children. Fifty-five compliant children who had amblyopia as a result of strabismus, anisometropia, or both, were treated with full-time (during all waking hours) occlusion of their good eye until no further improvement in the visual acuity of the amblyopic eye was observed on 3 consecutive monthly follow-up examinations. After this, part-time (4 hours per day) occlusion therapy was used randomly in 24 of 55 patients for 3 to 6 months for maintenance of the final visual acuity. All 55 patients had improved visual acuity after treatment. The mean improvement was 0.46 ± 0.24 logMAR unit (4.6 Snellen lines) which was statistically significant ( P < .0001). Maximum improvement was 0.90 logMAR unit (9 Snellen lines) in 2 patients. Patient age had no significant effect on mean improvement in visual acuity, although patients 14 to 15 years old showed a statistically significantly late improvement compared to those 11 years old ( P < .05). There was no change in the visual acuity of the good eyes. Thirty-two of the patients had a mean follow-up of 17.6 months after the cessation of full-time and maintenance occlusion therapy. Twenty-nine (91%) of the 32 patients maintained improved visual acuity, while 3 (9%) exhibited a regression in visual acuity. Maintenance occlusion therapy did not have a significant stabilizing impact on the improved visual acuity. The conclusion was that compliant, full-time occlusion effectively improves acuity in children 11 to 15 years old with amblyopia and that lasting effects can be achieved, with or without maintenance patching.—Michael D. Wagoner

There are no comments yet on this publication. Be the first to share your thoughts.


Seen <100 times