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Evaluation of progestational agents for postmenopausal hot flushes

Authors
Journal
International Journal of Gynecology & Obstetrics
0020-7292
Publisher
Wiley Blackwell (John Wiley & Sons)
Publication Date
Volume
20
Issue
2
Identifiers
DOI: 10.1016/0020-7292(82)90025-x
Keywords
  • Progestational Agents
  • Postmenopausal Hot Flushes
  • Medroxyprogesterone Acetate
  • Estrogen Therapy
  • Vasomotor Symptoms
  • Psychologic And Symptomatic Therapy
  • Estrogen Withdrawal
Disciplines
  • Medicine

Abstract

Abstract The role of progestational agents in the treatment of postmenopausal hot flushes has been evaluated in castrated women. Medroxyprogesterone acetate was found to be more potent and more effective than 17 hydroxyprogesterone caproate and is recommended as an acceptable substitute to estrogen therapy. The absence of serious side effects justifies its use for treating vasomotor symptoms, but a critical evaluation of its long-term effects is required.

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