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Antidiabetic activity of Trichosanthes cucumerina in normal and streptozotocin–induced diabetic rats

Authors
Publisher
Ivyspring International Publisher
Publication Date
Disciplines
  • Design
  • Medicine

Abstract

Aerial parts of Trichosanthes cucumerina (Family: Cucurbitaceae) are used in traditional medical systems for treatment of diabetes and other diseases. The present study was designed to experimentally evaluate the antidiabetic potential of a hot water extract (HWE) of T. cucumerina (TC) aerial parts. In normoglycemic rats, HWE mediated (a) a dose dependent reduction in fasting blood glucose (FBS) levels (by 35% at 4h post-treatment with dose of 750 mg/kg) and (b) a significant (P

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