The present contribution outlines several selected applications of the MEGAFLOW software at DLR, roughly according to the time-frame of the MEGAFLOW II project from 1998 - 2002. The majority of the applications is based on 3-dimensional viscous computations featuring the solution of the compressible Reynolds-averaged Navier-Stokes equation in combination with one or two transport equation turbulence models. The examples highlight a quite broad range of applications. This refers to onflow speed as well as the the mode of application, covering analysis as well as design and optimization tasks. In general a clear trend in the use of the MEGAFLOW system becomes visible. On the hand the analyses of very specific flow and/or aircraft details on overall configurations of increasing complexity is carried out. On the other hand more design and optimization applications are requested. For both types of applications the MEGAFLOW software has become an indispensable tool for the aerodynamic and also multi-disciplinary tasks of DLR.