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18F-FDG PET reveals unique features of large vessel inflammation in patients with Takayasu's arteritis.

Authors
  • Incerti, Elena1
  • Tombetti, Enrico2, 3
  • Fallanca, Federico1
  • Baldissera, Elena M3
  • Alongi, Pierpaolo1
  • Tombolini, Elisabetta2
  • Sartorelli, Silvia2, 3
  • Sabbadini, Maria Grazia2, 3
  • Papa, Maurizio4
  • De Cobelli, Francesco2, 4
  • Mason, Justin C5
  • Gianolli, Luigi1
  • Manfredi, Angelo A2, 3
  • Picchio, Maria6
  • 1 Unit of Nuclear Medicine, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy. , (Italy)
  • 2 Vita-Salute San Raffaele University, Milan, Italy. , (Italy)
  • 3 Unit of Internal Medicine and Clinical Immunology, IRCCS San Raffaele Scientific Institute, Milan, Italy. , (Italy)
  • 4 Department of Radiology, IRCCS San Raffaele Scientific Institute, Milan, Italy. , (Italy)
  • 5 Vascular Science and Rheumatology, Imperial College London and Imperial College Healthcare NHS Trust, London, UK.
  • 6 Unit of Nuclear Medicine, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy. [email protected] , (Italy)
Type
Published Article
Journal
European Journal of Nuclear Medicine
Publisher
Springer-Verlag
Publication Date
Feb 08, 2017
Identifiers
DOI: 10.1007/s00259-017-3639-y
PMID: 28180963
Source
Medline
Keywords
License
Unknown

Abstract

PET/CT reveals unique and fundamental features of arterial involvement in TA. PET/CT may be useful in the assessment of local inflammatory and vascular remodelling events independent of systemic inflammation during follow-up, even in lesions in which the arterial wall is <4 mm. The presence of arterial grafts is a potential confounder. Prospective studies are required to correlate PET findings with relevant clinical outcomes.

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