Affordable Access

Publisher Website

Damage control: regulating defenses against toxic metals and metalloids

Authors
Journal
Current Opinion in Microbiology
1369-5274
Publisher
Elsevier
Publication Date
Volume
12
Issue
2
Identifiers
DOI: 10.1016/j.mib.2009.02.003
Disciplines
  • Biology
  • Ecology

Abstract

Some elements are essential for life and others closely related to them are very toxic. In exploiting unique ecological niches many prokaryotes have evolved the means to defend themselves against and even to derive energy from deleterious elements. Toxic metal defense systems are related to those providing homeostasis of essential metals and metalloid elements. Expression of these multiprotein systems is costly but they must respond rapidly and, so, all are well controlled. Seven diverse families of metalloregulators are presently recognized for essential metal homeostasis in prokaryotes. Two of these, the ArsR and MerR families, figure more often than the others in controlling responses to toxic transition metals and metalloids. This review emphasizes recent advances in these two metalloregulator families and highlights emerging regulatory motifs of other types.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Toxic metals and metalloids in dietetic products.

on Croatian medical journal April 2003

How Saccharomyces cerevisiae copes with toxic meta...

on FEMS microbiology reviews November 2010

Evaluation of metals, metalloids, and ash mixture...

on Integrated Environmental Asses... January 2015
More articles like this..