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Radioisotope studies on the anemia produced by infection withFasciola hepatica

Authors
Journal
Experimental Parasitology
0014-4894
Publisher
Elsevier
Publication Date
Volume
5
Issue
5
Identifiers
DOI: 10.1016/s0014-4894(56)80006-4

Abstract

Summary Red cells labelled with P 32 and serum albumin labelled with I 131 have been used to study the anemia associated with F. hepatica infections in rabbits and to make an estimate of the amount of the daily blood loss. The blood loss as calculated from P 32 experiments is of sufficient magnitude to account for the anemia. When I 131-labelled serum albumin and P 32-labelled red cells were used simultaneously it was found that the P 32/I 131 ratio in the flukes was consistently higher than that in the blood. The use of radioisotope techniques in the study of this type of problem is discussed.

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