Abstract Obsessive compulsive disorder (OCD) patients often have lifetime comorbid anxiety and depressive disorders. Incidence of lifetime OCD in other anxiety disorder patients, however, has not been fully investigated. In the current study, a structured diagnostic interview was administered to 454 patients with OCD, panic agoraphobia, or social phobia. Results indicated a relatively high level of lifetime anxiety disorders in OCD subjects but a much lower rate of lifetime OCD in other anxiety-disorder patients. Lifetime depression was not found to be different across the groups. The results are discussed in terms of possible vulnerability factors associated with OCD.