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Taxol fromPestalotiopsis paucisetaVM1, an endophytic fungus ofTabebuia pentaphylla

Authors
Journal
Biomedicine & Preventive Nutrition
2210-5239
Publisher
Elsevier
Publication Date
Volume
1
Issue
2
Identifiers
DOI: 10.1016/j.bionut.2010.12.005
Keywords
  • Taxol
  • Pestalotiopsis Pauciseta
  • Endophyte

Abstract

Abstract Taxol is the world's first billion-dollar anticancer drug, and it is used to treat ovarian, breast, lung as well as head and neck cancers. The purpose of this work was to identify a taxol-producing endophytic fungus Pestalotiopsis pauciseta VM1 isolated from Tabebuia pentaphylla Hemsl. by morphological and molecular method. Pestalotiopsis pauciseta VM1 produced taxol, when grown in M1D medium and analysed by Thin Layer Chromatography (TLC), High Performance Liquid Chromatography (HPLC), Ultraviolet (UV), Infrared (IR) Spectroscopy and Mass Spectroscopy (MS).

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