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A chemoenzymatic approach to the taxoid BC-substructure

Authors
Journal
Tetrahedron
0040-4020
Publisher
Elsevier
Publication Date
Volume
52
Issue
17
Identifiers
DOI: 10.1016/0040-4020(96)00270-0
Keywords
  • Article

Abstract

Abstract The synthesis of a homochiral taxoid BC-unit containing the required functionalities on the B-ring periphery and a conveniently functionalized C-ring moiety by combination of enzymatic hydrolysis and the aldol-annelation-fragmentation sequence is described.

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