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On the MIAME Standards and Central Repositories of Microarray Data

Comparative and Functional Genomics
Hindawi Publishing Corporation
Publication Date
DOI: 10.1002/cfg.238
  • Research Article
  • Biology


cfg238.dvi Comparative and Functional Genomics Comp Funct Genom 2003; 4: 1. Published online in Wiley InterScience ( DOI: 10.1002/cfg.238 Editorial On the MIAME standards and central repositories of microarray data CFG has been approached, along with other jour- nals publishing in the area of genomics, by the Microarray Gene Expression Database (MGED) society. We have been urged to use its recommen- dations when deciding whether to accept a paper for publication. As frequent readers of this jour- nal will know, CFG supports the development and usage of standards and ontologies in genomics, as evidenced in this issue by our coverage of two key ontology meetings. It is the decision of our Editorial Board that, from this issue onwards, compliance with the Min- imum Information About a Microarray Experi- ment (MIAME; 1, 2) standards will be manda- tory — except in cases where a microarray is used to identify one, or a few, genes, and these indi- vidual genes are then the subject of much deeper analysis that validates their selection. In this latter case, the microarray is merely a ‘primary screen’ and, just as for a genetic screen, one wouldn’t nec- essarily publish all the data at once. On the issue of data submission to central repositories (ArrayExpress and GEO), CFG prefers to be, for now, less strict. We certainly encourage authors to submit their data to a central repository, and we will eventually make such deposition mandatory. This will apply when the set-up of the central databases has matured, and deposition is a straightforward process for any user. However, from now on, authors are obliged to make sure, and confirm to us in writing, that their entire data set will be available on the Internet, without charge or limitation, for at least 2 years from the date of publication, even if their data is not deposited centrally. In cases where it is not possible for authors to host their dataset, CFG will investigate providing access to the data on its own

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