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Soft tissue uptake of Tc99m-MDP in acute lymphoblastic leukemia

Authors
Journal
Clinical Imaging
0899-7071
Publisher
Elsevier
Publication Date
Volume
26
Issue
3
Identifiers
DOI: 10.1016/s0899-7071(01)00384-9
Keywords
  • Acute Lymphoblastic Leukemia
  • Hypercalcemia
  • Tc99M-Mdp
  • Soft Tissue Uptake
  • Bone Scintigraphy
Disciplines
  • Biology
  • Medicine

Abstract

Abstract Acute lymphoblastic leukemia (ALL) is associated rarely with hypercalcemia. This may be due to elevated levels of parathyroid hormone-related peptide (PTHrP). We report a case of an 18-year-old female patient who was presented with a pathological fracture of left intertrochanteric region. Bone scintigraphy was consistent with features of hypercalcemia associated with metastatic calcification. A bone marrow biopsy led to the diagnosis of ALL. The mechanism of hypercalcemia in ALL, metastatic calcification and soft tissue uptake of bone seeking agents in this case are discussed in detail.

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