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The transcription unit for poly(I) · poly(C)-induced human fibroblast interferon messenger RNA

Authors
Journal
Virology
0042-6822
Publisher
Elsevier
Publication Date
Volume
102
Issue
1
Identifiers
DOI: 10.1016/0042-6822(80)90090-2
Disciplines
  • Physics

Abstract

Abstract The size of the transcription unit for poly(I) · poly(C)-induced human fibroblast interferon mRNA was estimated by monitoring the inactivation of interferon mRNA synthesis by ultraviolet irradiation of induced FS-4 cell cultures. The transcription unit for human fibroblast interferon mRNA (12 S), which is itself approximately 850–900 residues long, is in the size range 4–11 kilobases.

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