The Lower Permian Patquía Formation is the youngest unit of the Paganzo Basin, western Argentina. The lower section consists of red mudstones, and fine- and coarse grained sandstones deposited in fluvial systems with extensive and thick floodplain deposits. These rocks contain a low-diversity and relatively abundant association of trace fossils suggesting the activity of a sub-superficial to superficial fauna. The association is characterized by Rusophycus carbonarius (Cubichnia), Cruziana problematica (Repichnia), and Palaeophycus tubularis (Domichnia) of the Scoyenia ichnofacies. Disarticulated fish remains are also present. The upper section is dominated by red, cross-bedded, medium- to fine-grained sandstones deposited in eolian systems that host a lowdiversity and low-abundance association of trace fossils that indicates the activity of a mainly superficial fauna. Tetrapod footprints (Chelichnus duncani, oval digit imprints, short parallel grooves, and sinusoidal grooves), horizontal to vertical burrows (Palaeophycus tubularis and Skolithos isp. respectively), and arthropod trackways are the typical components of these deposits. The association shows elements of the three presently proposed eolian ichnofacies (Chelichnus, Octopodichnus and Entradichnus ichnofacies) suggesting the necessity of revision and the possible integration of these separate ichnofacies into a single model. The record of fossil vertebrate tracks is uncommon in Lower Permian strata of South America. Therefore, the ichnologic record of the Patquía Formation is a significant contribution to the understanding of Lower Permian South American ichnofaunas.