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Composite synthetic vascular prosthesis design for small diameter artery replacement

TUE : Materials Technology (Mate) group
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  • Design
  • Engineering
  • Mathematics
  • Medicine


poster.dvi 12 /department of biomedical engineering PO Box 513, 5600 MB Eindhoven, the Netherlands Composite synthetic vascular prosthesis design for small diameter artery replacement C.H.G.A. van Oijen, F.N. van de Vosse, F.P.T. Baaijens Eindhoven University of Technology, Department of Biomedical Engineering, [email protected] Introduction Failure of small diameter (< 5 mm) synthetic prostheses is often contributed to a mechanical mismatch with the host artery [1], [2]. Our objectives: ✷ development of a small diameter synthetic vascular prosthesis which is mechanically compatible with the host artery ✷ design based on an experimentally validated computa- tional model Method Mechanical characterisation In an experimental setup the artery is subjected to inter- nal pressure being suspended under axial extension. Real- time diameter measurement is performed using Ultrasound. These experiments provide material properties in longitudi- nal and axial directions. The applied loading is dynamic to investigate viscoelastic properties. force transducer pressure tip catheter PMMA container ultra-sound probe specimen torque transducer Computational framework The model is based on a FE implementation of geometrically and physically nonlinear material. In- compressibility is incorporated using a mixed formulation and the balance equations are solved using an integrated method. constitutive model The matrix-fiber structure is modeled us- ing a new composite model: σ = −pI + τˆ + N∑ k=1 θk (ψk − �ek · τˆ · �ek)�ek�ek θ = 1/3 Initially a simplified analytical model is used to fit the exper- imental data. Prototype development The prototype consists of a viscoelastic matrix (hydrogel) which is reinforcedwith non-linear elastic fibers (Lycra) to ob- tain material properties that match those of arteries. Design parameters are derived from the numerical model to give an optimized fiber layout. The fibers are fully embedded in the matrix to give extra strength to the g

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