Mono-colonization with Lactobacillus acidophilus NCFM affects the intestinal metabolome as compared to germ-free mice

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Mono-colonization with Lactobacillus acidophilus NCFM affects the intestinal metabolome as compared to germ-free mice

Authors
Keywords
  • However
  • Every Single Species Of The Gut Microbiota Produce Low-Molecular-Weight Compounds That Are Absorbed
  • Very Few Studies Address The Host Metabolome As A Function Of Colonizing Bacteria
  • In This Study The Effect Of The Lactobacillus Acidophilus Ncfm Strain Was Investigated By Comparing
  • By Liquid-Chromatography Coupled To Mass Spectrometry
  • We Were Able To Show That The Metabolome Differed Between The Mono-Colonized And Germ-Free Mice
  • Not Only In Ileum
  • Caecum And Colon
  • But Also In Plasma And Liver
  • These Observations Suggest That L
  • Acidophilus Ncfm Highly Influence The Metabolism In Multiple Compartments
  • Underlying That The Gut Microbiota Metabolism Affects The Host Systemic Metabolism

Abstract

Mono-colonization with Lactobacillus acidophilus NCFM affects the intestinal metabolome as compared to germ-free mice - DTU Orbit (27/05/14) Mono-colonization with Lactobacillus acidophilus NCFM affects the intestinal metabolome as compared to germ-free mice - DTU Orbit (27/05/14) Roager HM, Sulek K, Skov K, Frandsen HL, Smedsgaard J, Wilcks A, Hjort Skov T, Granato Villas-Boas S, Licht TR. 2013. Mono-colonization with Lactobacillus acidophilus NCFM affects the intestinal metabolome as compared to germ-free mice. Abstract from Copenhagen Bioscience Conference – Genomics in metabolism, Snekkersten, Denmark.

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