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DNA-Protein Interactions: Flip out and modify

Authors
Journal
Current Biology
0960-9822
Publisher
Elsevier
Publication Date
Volume
4
Issue
3
Identifiers
DOI: 10.1016/s0960-9822(00)00057-9
Keywords
  • Dispatch
Disciplines
  • Biology

Abstract

Abstract The crystal structure of a complex between a methyltransferase and DNA shows that, remarkably, the target cytosine base is swung out of the double helix and located next to the enzyme's S-adenosyl-L-homocysteine cofactor.

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