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Determination of nevirapine in the presence of cucurbit(7)uril with a gold electrode

Authors
Publisher
International Association of Physical Chemists; [email protected]
Publication Date
Source
Legacy
Keywords
  • Antiretroviral
  • Voltammetry
  • Tablets
  • Urine
Disciplines
  • Chemistry

Abstract

The electrochemical oxidation of nevirapine, an anti-HIV drug, at a gold electrode was studied by voltammetric techniques. Nevirapine showed a signal that interfered with a working electrode wave. This interference was solved by the use of cucurbit(7)uril allowing nevirapine to be determined in tablets (80.4 % recovery, presence of stavudine and lamivudine) and urine (98.4 %).

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