Affordable Access

Publisher Website

Theoretical models for cooperative binding—I. one-site creator of binding sites

Authors
Journal
Mathematical Biosciences
0025-5564
Publisher
Elsevier
Publication Date
Volume
41
Identifiers
DOI: 10.1016/0025-5564(78)90036-6
Disciplines
  • Mathematics

Abstract

Abstract A general mathematical model is derived for the description of positive cooperativity in ligand-macromolecular interactions resulting from the creation of new sites. The model makes no assumptions regarding the mechanism of the creation of new sites, but does assume a true ligand-induced creation of the new sites. Theoretical curves are presented for specific cases of the model showing the manifestations of the creation of new sites.

There are no comments yet on this publication. Be the first to share your thoughts.