Affordable Access

in vitro Decellularization of Rabbit Lung Tissue

Authors
Publisher
Royan Institute
Publication Date
Keywords
  • Research Article
  • Cellular And Molecular Science
  • Biology
Disciplines
  • Design
  • Engineering
  • Medicine

Abstract

Objective: The bioscaffold can be used in tissue engineering and regenerative medicine. The scaffolds used in tissue engineering must have high porosity to facilitate accelerated angiogenesis for feeding cells and repelling cell waste outside the scaffold. In this experimental study, we attempted to produce lung three-dimensional scaffold and assay its effect on cell penetration and migration. Materials and Methods: In an experimental study, rabbit lung tissue was decellularized and used as a scaffold for rabbit blastema cells. The scaffolds were studied on the 15th day after culturing. Results: Microscopic features revealed high porosity in the lung tissue scaffold. Electron microscopic imaging also showed collagen and elastin were intact, which are important properties in scaffolds designed for tissue engineering. Migration and permeation of blastema cells into the lung tissue scaffold was also observed. Conclusion: Rabbit lung tissue scaffolds have high porosity. Blastema cells successfully migrated toward and permeated the scaffold inside.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

LIPID SYNTHESIS BY RABBIT LUNG TISSUE IN VITRO.

on The American journal of physio... January 1965

Free fatty acid production by rabbit lung tissue i...

on The American journal of physio... October 1961
More articles like this..