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The nutrition of choline, carnitine, and related compounds in the blowfly,Phormia reginaMeigen

Authors
Journal
Journal of Insect Physiology
0022-1910
Publisher
Elsevier
Publication Date
Volume
10
Issue
6
Identifiers
DOI: 10.1016/0022-1910(64)90088-5

Abstract

Abstract Fifteen choline analogues were tested as substitutes for choline in the larval diet of Phormia regina. From the results the structural requirements for an adequate choline substitute are further defined. The choline analogue, (CH 3) 3+NCH 2CH 2CH 2OH, although not an inhibitor in the presence of choline, inhibits growth when choline is replaced in the diet by carnitine or γ-butyrobetaine. This compound presumably inhibits one of the reactions which metabolizes carnitine or γ-butyrobetaine to β-methyl choline.

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