Affordable Access

Publisher Website

Morphologic changes during hypertension

Authors
Journal
The American Journal of Cardiology
0002-9149
Publisher
Elsevier
Publication Date
Volume
63
Issue
6
Identifiers
DOI: 10.1016/0002-9149(89)90397-4
Disciplines
  • Medicine

Abstract

Abstract Circulation to the brain is greatly affected by hypertension and by its treatment. Neurologic dysfunction is prominent among the complications of increased arterial pressure and is also most susceptible to preventive antihypertensive therapy. The upward resetting of the limits of autoregulation of cerebral blood flow in hypertension is probably due largely to structural thickening of the walls (hyaline arteriosclerosis) of the resistance vessels. Other consequences of hypertensive vascular lesions in the brain include increased formation of atheroma, lacunae and lacunar infarction, cerebral infarction, multi-infarct dementia and Binswanger's disease. There is also an association between hypertension and hemorrhagic strokes, namely, subarachnoid and intracerebral hemorrhage. Brain lesions are also prominent in malignant hypertension and hypertensive encephalopathy. Antihypertensive treatment, especially if intensive, can result in boundary zone ischemia in the brain if arterial pressure decreases steeply.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Morphologic changes during hypertension.

on The American Journal of Cardio... Feb 02, 1989

Morphologic and functional changes of the aortic i...

on American Journal Of Pathology August 1979

Morphological functional changes of aortic endothe...

on Progress in biochemical pharma... 1977
More articles like this..