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Overexpression of theBCL2gene in a Sertoli–Leydig cell tumor of the ovary: a pathologic and cytogenetic study

Authors
Journal
Cancer Genetics and Cytogenetics
0165-4608
Publisher
Elsevier
Publication Date
Volume
148
Issue
2
Identifiers
DOI: 10.1016/s0165-4608(03)00276-0

Abstract

Abstract A case of virilizing ovarian Sertoli–Leydig cell tumor overexpressing the BCL2 gene and including a novel clonal chromosomal rearrangement of chromosome 18, der(5)t(5;18)(p13;q12),+6,+12, der(18)r(5;18)(p15.3p13;p11.3q12) is described. Further studies of these rare tumors are necessary to ascertain the significance of the findings.

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