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Catalyst structure and the enantioselective cyclopropanation of alkenes by copper complexes of biaryldiimines: the importance of ligand acceleration

Authors
Journal
Tetrahedron Asymmetry
0957-4166
Publisher
Elsevier
Publication Date
Volume
12
Issue
7
Identifiers
DOI: 10.1016/s0957-4166(01)00157-4

Abstract

Abstract The use of chiral non-racemic biaryl copper(I) complexes in the enantioselective cyclopropanation of a number of olefins with either ethyl or tert-butyl diazoacetate is described. Lack of ligand acceleration and the presence of equilibrium amounts of catalytically active uncomplexed Cu(I) ions account for lowered enantioselectivity when using certain ligands.

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