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Influenza B Viruses with Mutation in the Neuraminidase Active Site, North Carolina, USA, 2010–11

Authors
Publisher
Centers for Disease Control and Prevention
Publication Date
Volume
17
Issue
11
Identifiers
DOI: 10.3201/eid1711.110787
Keywords
  • Dispatch
Disciplines
  • Medicine

Abstract

Oseltamivir is 1 of 2 antiviral medications available for the treatment of influenza B virus infections. We describe and characterize a cluster of influenza B viruses circulating in North Carolina with a mutation in the neuraminidase active site that may reduce susceptibility to oseltamivir and the investigational drug peramivir but not to zanamivir.

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