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Assays for insulin-like growth factors and their binding proteins: Practicalities and pitfalls

Authors
Journal
The Journal of Pediatrics
0022-3476
Publisher
Elsevier
Publication Date
Volume
128
Issue
5
Identifiers
DOI: 10.1016/s0022-3476(96)70012-4
Disciplines
  • Biology
  • Medicine

Abstract

Abstract Insulin-like growth factors (IGFs) are growth hormone-dependent anabolic peptides that circulate in biologic fluids complexed to a family of IGF binding proteins. Measurement of the serum concentrations of IGF peptides and IGF binding proteins has proved to be an effective means of evaluating functional growth hormone status and makes it possible to establish a diagnosis of IGF deficiency. (J P EDIATR 1996;128:S52-7)

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