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Inducible and constitutive nucleoside-binding sites in Escherichia coli: differential inhibition by nucleoside analogues

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PMC

Abstract

Constitutive and inducible nucleoside-binding sites on the surface of the cells of E. coli B have different patterns of inhibition by nucleoside analogues. 1(β-D-Ribofuranosyl)-4-aminopyrimidine-6-one and isoguanosine preferentially inhibit the inducible binding sites while showdomycin and N4-dimethylcytidine interfere more strongly with the constitutive function.

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