Affordable Access

Publisher Website

trans-2-Aminocyclohexanols as pH-triggers for conformationally controlled crowns and podands

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
45
Issue
42
Identifiers
DOI: 10.1016/j.tetlet.2004.09.004
Keywords
  • Trans-2-Aminocyclohexanol
  • Ph-Switch
  • Cyclohexano Crown Ether
  • Conformations

Abstract

Abstract Protonation of trans-2-aminocyclohexanols leads to dramatic conformational changes: due to an intramolecular hydrogen bond a conformer with equatorial position of ammonio- and hydroxy-groups becomes predominant. The trans-2-aminocyclohexanol moiety has been used for pH-induced conformational switching of a crown ether and a podand.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Synthesis, structure and application of a new clas...

on Journal of Molecular Catalysis... Jan 01, 2008

In vivo nuclear Ca2+-ATPase phosphorylation trigge...

on Biochemical and Biophysical Re... Jan 01, 2003

Conformationally controlled intramolecular charge...

on The Journal of Organic Chemist... Oct 04, 2002
More articles like this..