A mathematical model is analyzed in order to study the effects of Soret, Dufour, chemical reaction, thermal radiation and volumentric heat generation/absorption on mixed convection stagnation point flow on an Iso-thermal vertical plate in a porous media. The governing partial differential equations are transformed into set of coupled ordinary differential equations, which are solved numerically using Runge-Kutta sixth order method along with shooting technique. The physical interpretation to this expression is assigned through graphs and tables for the wall shear stress , Nusselt number and Sherwood number . Results were compared with the existing literature and showed a perfect agreement. Similarly, results showed that the fields were influenced appreciably by the effects of the governing parameters: Soret number Sr, Dufour number Df, chemical reaction parameter γ, thermal radiation parameter Ra, order of reactions n, thermal Grashof number GT, solutal Grashof number GC, Prandtl number Pr, permeability parameter K, rate of heat generation/absorption parameter S, and magnetic field strength parameter M. It was evident that for some kind of mixtures such as the light and medium molecular weight, the Soret and Dufour’s effects should be considered as well.