Abstract Adolescent females, particularly blacks and those living in the southern United States, are considered to be at high nutritional risk. The findings of a southern regional study involving 550 black and 691 white adolescent girls are compared to those of subjects of similar ages included in national surveys. Black subjects in the regional study had higher blood pressure values than whites; race differences were observed for body weight, body mass indexes, and arm muscle areas. Girls in the regional as well as the national survey reported consuming low quantities of folate, vitamin B-6, zinc, iron, calcium, and magnesium. The majority of the subjects in the regional study reported having both afternoon and evening snacks. Blacks included in the regional study had higher plasma total and high-density lipoprotein-cholesterol concentrations than the whites. Specific nutritional problems of white and black girls included in the regional study were with regard to folate, vitamin B-6, and zinc as indicated by biochemical analyses.