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Optical resolution of tricarbonyl(1-carboxycyclohexa-1,3-diene) iron and the absolute configuration of the products

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
21
Issue
31
Identifiers
DOI: 10.1016/0040-4039(80)88014-2

Abstract

Abstract Resolution of the acid ( 1 ) (shown as the (+)-isomer) into its optically pure (+) and (−) isomers and reduction of the CO 2H yields the 2-Me derivative ( 2 ) (shown as the (−)-isomer). The absolute configuration of ( 2 ) is defined by conversion of the salt ( 3 ) of known configuration into ( 2 ) and ( 4 ). This is the first resolution leading to preparation of pure complexes of known absolute configuration.

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