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Lead nitrate induced hepato renal toxicity in the adult albino rates

Rajshahi University Zoological Society
Publication Date
  • Zoology
  • Lead
  • Hepatotoxicity
  • Renal Toxicity
  • Albino Rates
  • Enzymes
  • Lipids
  • Biology
  • Chemistry
  • Medicine


Non-protein nitrogen compound poisoning in cattle Univ. j. zool. Rajshahi Univ. Vol. 31, 2012 pp. 65-68 ISSN 1023-6104 © Rajshahi University Zoological Society Non-protein nitrogen compound poisoning in cattle Amir Hossan Shaikat, Mohammad Mahmudul Hassan, S. K. M. Azizul Islam, Shahneaz Ali Khan, Md. Ahasanul Hoque, Md. Nurul Islam and Mohammad Belayet Hossain, Department of Physiology, Biochemistry and Pharmacology, Chittagong Veterinary and Animal Sciences University Abstract : The study was carried out in Chittagong Veterinary and Animal Sciences University (CVASU), Chittagong to find out the causes of sudden death of cattle in the Military Dairy Farm, Chittagong. To explore the cause of death, clinical history, clinical signs were recorded. Finally, postmortem was done and samples were collected for laboratory diagnosis. The ruminal pH was 9.0 and the clinical history along with signs suggests possible non-protein nitrogenous compound poisoning. The laboratory diagnosis coincides with nitrate poisoning which focuses possible relationship between non-protein nitrogenous compound and nitrate poisoning. The study recommends maintaining proper cautions to use urea in concentrate feed. Key words : Non-protein, urea, ammonia, nitrate, poison Introduction Urea poisoning is one of the common toxicities found in ruminants especially cattle. It is used as an alternative nonprotein nitrogen (NPN) source in ruminant diet and its nitrogen is liberated as ammonia in rumen and then the released ammonia is used by rumen microbes to synthesize their own protein. But in urea, nitrogen can be replaced by up to 16% of the dietary nitrogen along with 2 or more feeds for dairy cows (Froslie, 1977). Dietary urea has been used for decades as an effective and inexpensive source of nitrogen for ruminal microbial utilization. It is rapidly hydrolyzed upon entry into the rumen resulting in peak rumen ammonia concentrations within

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