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Solidifying liquid with novel initiation system for detachable balloon catheters

Authors
Journal
Biomaterials
0142-9612
Publisher
Elsevier
Publication Date
Volume
13
Issue
13
Identifiers
DOI: 10.1016/0142-9612(92)90111-z
Keywords
  • Endovascular Surgery
  • Balloon Catheters
  • P(Hema)
  • Glucose Oxidase
  • Solidifying Liquid
Disciplines
  • Chemistry
  • Medicine

Abstract

Abstract In endovascular surgery, to permanently hinder blood inflow into an aneurysm for example, a catheter is percutaneously introduced into an artery and the balloon is positioned and inflated by a solidifying liquid and then released into the diseased part. A novel solidifying liquid for the inflated balloon curable under the continuous feeding of oxygen through the wall of the balloon is described here. Glucose oxidase which oxidizes glucose producing hydrogen peroxide was used for polymerization of the solidifying liquid. This solidifying liquid cured even in the presence of oxygen and water. It was radiopaque when mixed with the iodinated X-ray contrast chemical iopamidol. In addition, the solidified liquid had appropriate mechanical properties. The endovascular surgery could be carried out safely using it.

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