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Prevention of the adhesion ofPseudomonas aeruginosato human buccal epithelial cells

Authors
Journal
International Journal of Pharmaceutics
0378-5173
Publisher
Elsevier
Publication Date
Volume
53
Issue
3
Identifiers
DOI: 10.1016/0378-5173(89)90320-7
Keywords
  • Pseudomonas Aeruginosa
  • Adhesion
  • Human Buccal Epithelial Cell
  • Protamine

Abstract

Abstract The influence of protamine on the adhesion of Pseudomonas aeruginosa to human buccal cells was investigated using 2 collection strains and 5 other strains isolated from the hospital environment. The serotype and pyocin type of the strains was established and their antibiotic sensitivity determined. For concentrations lower than 100 μg/ml there was a decrease in adhesion correlating with protamine concentration. Maximum inhibition was reached at about 100 μg/ml.

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