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Rebuilding the Nigrostriatal Dopamine Pathway: 30 Years and Counting

Authors
Journal
Experimental Neurology
0014-4886
Publisher
Elsevier
Volume
256
Identifiers
DOI: 10.1016/j.expneurol.2014.03.011

Abstract

Highlights • Issues surrounding reconstruction of the nigrostriatal dopamine pathway are reviewed. • Early attempts using bridges of cells or growth factors achieved modest success. • Molecular factors active during development offer new and potentially powerful tools. • A perspective on future directions and goals of reconstruction is presented.

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