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Synthesis of atovaquone

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
39
Issue
42
Identifiers
DOI: 10.1016/s0040-4039(98)01691-8

Abstract

Abstract A short synthesis of atovaquone 1 is achieved via the radical coupling of the trans-1,4-substituted cyclohexyl mono-oxalate 2 and 2-chloronapthoquinone under phase transfer conditions.

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