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Immunological relatedness between β-galactosidases of different bacterial origins

Authors
Journal
Molecular Immunology
0161-5890
Publisher
Elsevier
Publication Date
Volume
16
Issue
6
Identifiers
DOI: 10.1016/0161-5890(79)90108-1
Disciplines
  • Biology

Abstract

Abstract Antibodies directed against Escherichia coli and plasmid coded β-galactosidases react strongly with all heterologous enzymes, indicating great structural similarity between these proteins. The quantitative differences in the extent of cross-reactivity are interpreted in terms of multiplicity of exposed common antigenic determinants, dependent upon the conformation the different enzymes assume. The results are consistent with the hypothesis of a common origin of these β-galactosidases.

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