Affordable Access

deepdyve-link
Publisher Website

β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo.

Authors
  • Daaboul, Hamid E1
  • Daher, Costantine F2
  • Taleb, Robin I2
  • Boulos, Joelle2
  • Bodman-Smith, Kikki1
  • Boukamp, Petra3, 4
  • Shebaby, Wassim N2
  • Dagher, Carol5
  • El-Sibai, Mirvat2
  • Mroueh, Mohamad A6
  • 1 Department of Microbial Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
  • 2 Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, Byblos, Lebanon. , (Lebanon)
  • 3 Deutsches Krebsforschungszentrum DKFZ, German Cancer Research Center, Genetics of Skin Carcinogenesis, Heidelberg, Germany. , (Germany)
  • 4 IUF-Leibniz Research Institute for Environmental Medicine, Duesseldorf, Germany. , (Germany)
  • 5 School of Medicine, Lebanese American University, Byblos, Lebanon. , (Lebanon)
  • 6 Department of Pharmaceutical Sciences, School of Pharmacy, Lebanese American University, Byblos, Lebanon. , (Lebanon)
Type
Published Article
Journal
The Journal of pharmacy and pharmacology
Publication Date
Nov 01, 2017
Volume
69
Issue
11
Pages
1552–1564
Identifiers
DOI: 10.1111/jphp.12796
PMID: 28872682
Source
Medline
Keywords
License
Unknown

Abstract

In conclusion, HC treatment induced cell cycle arrest (low dose) and promoted apoptosis partly via inhibition of the MAPK/ERK and PI3K/AKT pathways with no significant toxicity to laboratory mice.

Report this publication

Statistics

Seen <100 times