Novel Conserved Genotypes Correspond to Antibiotic Resistance Phenotypes of E. coli Clinical Isolates
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Early assessment of anxiety and behavioral response to novel swine-origin influenza A(H1N1)
Since late April, 2009, a novel influenza virus A (H1N1), generally referred to as the "swine flu," has spread around the globe and infected hundreds of thousands of people. During the first few days after the initial outbreak in Mexico, extensive media coverage together with a high degree of uncertainty about the transmissibility and mortality rat...
Auto-oscillation and narrow spectral lines in spin-torque oscillators based on MgO magnetic tunnel junctions Bis
Published in Journal of Test Deposits
We demonstrate spin-torque induced coherent auto-oscillation in magnetic tunnel junctions of composition PtMn/CoFe/Ru/CoFeB/MgO/CoFeB and of low resistance-area product. At the generation threshold, we observe a strong line narrowing down to 6 MHz at 300 K and a dramatic increase in oscillator power, yielding spectrally pure oscillations with extre...
The ALICE online data storage system
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The ALICE (A Large Ion Collider Experiment) Data Acquisition (DAQ) system has the unprecedented requirement to ensure a very high volume, sustained data stream between the ALICE Detector and the Permanent Data Storage (PDS) system which is used as main data repository for Event processing and Offline Computing. The key component to accomplish this ...
Synchrotron Reveals Early Triassic Odd Couple: Injured Amphibian and Aestivating Therapsid Share Burrow.
Published in PloS one
Fossorialism is a beneficial adaptation for brooding, predator avoidance and protection from extreme climate. The abundance of fossilised burrow casts from the Early Triassic of southern Africa is viewed as a behavioural response by many tetrapods to the harsh conditions following the Permo-Triassic mass-extinction event. However, scarcity of verte...
Numerical discrimination by frogs (Bombina orientalis)
Published in Animal Cognition
Evidence has been reported for quantity discrimination in mammals and birds and, to a lesser extent, fish and amphibians. For the latter species, however, whether quantity discrimination would reflect sensitivity to number or to the continuous physical variables that covary with number is unclear. Here we reported a series of experiments with frogs...
Use of kind information for object individuation in young domestic chicks.
Published in Animal cognition
In this paper, we studied the ability of newborn chicks to use kind information (sortal objects) provided by social and food attractors to determine the number of distinct objects present in an event (object individuation). Newly hatched chicks were reared with five imprinting objects and were fed mealworms. Chicks' spontaneous tendency to approach...
Systematic review of the side effects associated with tyrosine kinase inhibitors used in the treatment of gastrointestin...
Published in Critical reviews in oncology/hematology
Tyrosine kinase inhibitors (TKIs) have revolutionised the treatment of advanced gastrointestinal stromal tumours (GISTs). Imatinib is approved as first line therapy and sunitinib is used in cases of imatinib resistance or intolerance. Compared with conventional treatments, TKIs are delivered over longer periods of time and are more specific in thei...
Influence of proteolytic-antiproteolytic enzymes and prooxidative-antioxidative factors on proteoglycan alterations in c...
Published in Clinical biochemistry
Proteoglycan/glycosaminoglycan alterations in JIA patients, which are stimulated by MMP-3 and reactive oxygen species (ROS), indicate rather systemic disturbance of extracellular matrix metabolism, and not merely local changes which occur in articular structures. Given the destructive potential of ROS and MMPs and their hyperexpression in JIA, inhi...
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
The innate immune system senses nucleic acids by germline-encoded pattern recognition receptors. RNA is sensed by Toll-like receptor members TLR3, TLR7 and TLR8, or by the RNA helicases RIG-I (also known as DDX58) and MDA-5 (IFIH1). Little is known about sensors for cytoplasmic DNA that trigger antiviral and/or inflammatory responses. The best char...
