Aaij, R. Beteta, C. Abellán Adeva, B. Adinolfi, M. Aidala, C. A. Ajaltouni, Z. Akar, S. Albicocco, P. Albrecht, J. Alessio, F.
...
Published in
The European Physical Journal C
A search for the rare leptonic decay B+→μ+μ-μ+νμ\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${{{B} ^+}} \!\rightarrow {\mu ^+} {\mu ^-} {\mu ^+} {{\upnu } _\mu } $$\...
Kriegsman, Barry Vangala, Pranitha Chen, Benjamin J. Meraner, Paul Brass, Abraham L. Garber, Manuel Rock, Kenneth L.
To arise and progress, cancers need to evade immune elimination. Consequently, progressing tumors are often MHC class I (MHC-I) low and express immune inhibitory molecules, such as PD-L1, which allows them to avoid the main antitumor host defense, CD8(+) T cells. The molecular mechanisms that led to these alterations were incompletely understood. I...
Yuan, Yiyang Lapane, Kate L. Baek, Jonggyu Jesdale, William M. Ulbricht, Christine M.
OBJECTIVES: To examine the association between nursing home (NH) quality and new onset of depression and severity of depressive symptoms in a national cohort of long-stay NH residents in the United States. DESIGN: Cohort study. SETTING AND PARTICIPANTS: 129,837 long-stay residents without indicators of depression admitted to 13,921 NHs. METHODS: NH...
Keeler, Allison M. Flotte, Terence R.
The recent market approvals of recombinant adeno-associated virus (rAAV) gene therapies in Europe and the United States are landmark achievements in the history of modern science. These approvals are also anticipated to herald the emergence of a new class of therapies for monogenic disorders, which had hitherto been considered untreatable. These ev...
Sommerer, Sabine
Johnson, Janel O. Chia, Ruth Landers, John E.
SPTLC1 encodes a critical subunit of serine palmitoyltransferase, the enzyme catalyzing the first and rate-limiting step in de novo sphingolipid biosynthesis, and mutations in this gene are known to cause hereditary sensory autonomic neuropathy, type 1A. Using exome sequencing, we identified a de novo variant in SPTLC1 resulting in a p.Ala20Ser ami...
Bradley, Evan S. Liss, David Carreiro, Stephanie P. Brush, David Eric Babu, Kavita M.
Introduction: Despite widespread recognition of the opioid crisis, opioid overdose remains a common reason for Emergency Department (ED) utilization. Treatment for these patients after stabilization often involves the provision of information for outpatient treatment options. Ideally, an ED visit for overdose would present an opportunity to start t...
Rosen, Max P. Walz, J. Matthias
The study by Urman et al (1) in this issue of Radiology addresses the effect of respiratory compromise among inpatients undergoing interventional radiology (IR) procedures performed with moderate sedation. The study was conducted by using a national all-payer database and included data from over 500 000 patients across 853 hospitals, collected duri...
Silvas, Tania V. Schiffer, Celia A.
Nucleic acid editing enzymes are essential components of the human immune system that lethally mutate viral pathogens and somatically mutate immunoglobulins. Among these enzymes are cytidine deaminases of the apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like (APOBEC) super family, each with unique target sequence specificity and subc...
Wewiorski, Nancy J. Gorman, Jay A. Ellison, Marsha Langer Hunt, Marcia G. Evans, Leigh Charns, Martin P.
OBJECTIVE: A site visit protocol was developed to assess recovery promotion in the organizational climate and culture of programs for veterans with serious mental illnesses. METHOD: The protocol was pilot-tested in 4 programs: 2 that had scored high on the pilot version of a staff survey measure of program-level recovery promotion and 2 that had sc...
